| Michael & Susan Dell Foundation | Austin | $4,322,649,164 |
| Laura and John Arnold Foundation | Houston | $687,258,876 |
| Communities Foundation of Texas | Dallas | $341,607,358 |
| Greater Houston Community Foundation | Houston | $293,284,617 |
| Kate Marmion Charitable Foundation | San Antonio | $281,468,214 |
| Brown Foundation Inc | Houston | $183,844,252 |
| Rose Family Foundation | Dallas | $166,425,248 |
| Moody Foundation | Galveston | $162,839,323 |
| The Dallas Foundation | Dallas | $159,979,237 |
| Carl and Marilynn Thoma | Dallas | $156,765,718 |
| Methodist Primary Care Group | Houston | $144,241,299 |
| J E and L E Mabee Foundation Inc | Midland | $132,447,203 |
| Houston Endowment Inc | Houston | $122,609,629 |
| James N McCoy Foundation | Wichita Falls | $108,227,598 |
| San Antonio Area Foundation | San Antonio | $108,029,836 |
| Community Foundation of North Texas | Fort Worth | $96,375,864 |
| Dallas Center for the Performing Arts Foundation Inc | Dallas | $83,591,836 |
| Scharbauer Foundation Inc | Midland | $79,698,649 |
| United Way of Greater Houston | Houston | $79,626,568 |
| Austin Community Foundation | Austin | $79,280,742 |
| Fmh Foundation | Midland | $73,532,830 |
| Dallas Jewish Community Foundation | Dallas | $68,111,732 |
| Philecology Foundation | Fort Worth | $67,820,459 |
| Kinder Foundation | Houston | $67,607,405 |
| Dian Graves Owen Foundation | Abilene | $63,966,248 |
| Permian Basin Area Foundation | Midland | $60,538,071 |
| Karakin Foundation | Abilene | $58,001,484 |
| San Angelo Area Foundation | San Angelo | $55,338,463 |
| United Way of Metropolitan Dallas Inc | Dallas | $52,493,218 |
| More Than the Move Foundation | Houston | $51,995,278 |
| Robert A Welch Foundation 062491 | Houston | $47,618,127 |
| Dan L Duncan Family Foundation | Houston | $46,632,137 |
| Mulva Family Foundation | Austin | $45,133,111 |
| United Way of San Antonio & Bexar County | San Antonio | $44,166,866 |
| Holdsworth Center | Austin | $40,223,613 |
| Community Foundation of Abilene | Abilene | $36,088,689 |
| Centerpoint Energy Foundation Inc | Houston | $34,146,675 |
| W W Caruth Jr Foundation | Dallas | $33,660,755 |
| Houston Jewish Community Foundation | Houston | $32,520,743 |
| Marvy Finger Family Foundation | Houston | $32,082,328 |
| Eula Mae and John Baugh Foundation | San Antonio | $31,413,924 |
| Rainwater Charitable Foundation | Fort Worth | $28,931,463 |
| Ting Tsung and Wei Fong Chao Foundation | Houston | $28,005,470 |
| Texas Instruments Foundation | Dallas | $26,332,299 |
| Amarillo Area Foundation Inc | Amarillo | $26,310,718 |
| Legett Foundation | Abilene | $24,301,725 |
| Kickapoo Springs Foundation | Abilene | $24,258,103 |
| Nelda C and Hj Lutcher Stark Foundation | Orange | $23,940,643 |
| Heavenly Fathers Foundation | Cisco | $23,195,750 |
| The Powell Foundation | Houston | $22,834,407 |
| Wildcat Foundation | Fort Worth | $21,378,096 |
| Eleanor Crook Foundation | San Marcos | $20,527,801 |
| University of North Texas Foundation Inc | Denton | $20,497,479 |
| Musk Foundation | Austin | $20,491,653 |
| The@Sarah and Ross Perot Jr Foundation | Dallas | $20,205,284 |
| The Cullen Foundation | Houston | $18,825,483 |
| Tom T East Sr & Alice K East & Alice H East & Robert C East Wildl | San Antonio | $16,451,180 |
| Albert and Margaret Alkek Foundation | Houston | $15,269,215 |
| Rees-Jones Foundation | Dallas | $14,317,434 |
| Ewing Halsell Foundation | San Antonio | $14,131,547 |
| Lyda Hill Foundation | Dallas | $13,669,899 |
| Scott & White Healthcare | Dallas | $13,224,219 |
| Rowling Foundation | Dallas | $13,116,273 |
| The Pogue Family Foundation | Dallas | $13,009,676 |
| Klesse Foundation | San Antonio | $12,523,003 |
| Addy Foundation | Dallas | $12,282,896 |
| Charles Butt Foundation | San Antonio | $11,244,928 |
| Coulter Family Foundation | Fort Worth | $11,091,311 |
| Stanley E Fulton Family Foundation | Dallas | $10,824,084 |
| Woodforest Charitable Foundation | The Woodlands | $10,404,698 |
| Jay Pritzker Foundation | Houston | $9,950,464 |
| Greehey Family Foundation | San Antonio | $8,931,125 |
| Tres Grace Family Foundation | San Antonio | $8,606,152 |
| The Usaa Foundation Inc | San Antonio | $8,456,521 |
| Bnsf Foundation | Fort Worth | $7,883,990 |
| Simon Bolivar Foundation Inc | Houston | $7,817,067 |
| John L Santikos Charitable Foundation | San Antonio | $7,681,977 |
| Impetus Foundation | San Antonio | $7,635,616 |
| Gene and Jerry Jones Family-Dallas Cowboys Charities | Frisco | $7,573,453 |
| Hamon Charitable Foundation | Dallas | $7,214,820 |
| Harvey E Najim Charitable Foundation | San Antonio | $7,187,819 |
| Jlh Foundation | Katy | $6,825,287 |
| The Lanier Theological Library Foundation | Houston | $6,715,527 |
| Hildebrand Foundation | Houston | $6,249,208 |
| Santander Consumer USA Inc Foundation | Dallas | $5,996,762 |
| Hector and Gloria Lopez Foundation | Austin | $5,112,181 |
| Highland Dallas Foundation Inc | Dallas | $4,709,490 |
| Meadows Foundation Incorporated | Dallas | $3,668,203 |
| Mercedes T Bass Charitable Corporation | Fort Worth | $3,247,847 |
| Hirsch Family Foundation | Dallas | $1,254,823 |
| Hobby Family Foundation | Houston | $1,104,680 |
| Srb Charitable Corporation | Fort Worth | $681,691 |
| Gerald J Ford Family Foundation | Dallas | $362,606 |
| Once Upon A Time Foundation | Fort Worth | $138,880 |
| Ainslie Foundation | Dallas | $87,691 |