| Battelle Memorial Institute | $13,526,408,187 |
| Ohiohealth Corporation | $5,723,845,185 |
| Nationwide Childrens Hospital | $4,325,096,802 |
| Ohiohealth Corporation | $2,182,011,764 |
| Mount Carmel Health System | $1,427,168,597 |
| Ohio State University Physicians Inc | $1,231,249,686 |
| Buckeye Power Inc | $915,533,213 |
| Jobsohio Beverage System | $702,077,129 |
| Mount Carmel Health Plan Inc | $598,543,717 |
| Columbus Foundation | $411,632,853 |
| Ohio State University Foundation | $378,949,364 |
| Jobsohio | $313,472,056 |
| National Youth Advocate Program | $302,719,234 |
| Pediatric Academic Association Inc Department of Pediatrics B-132 | $182,336,817 |
| Capital University | $121,510,087 |
| Franklin University | $111,960,173 |
| Hospital Properties Inc | $91,036,675 |
| Equitas Health Inc | $86,300,739 |
| 64 Telhio Credit Union Inc | $85,291,658 |
| Ohio Education Assn | $73,811,500 |
| Young Mens Christian Association of Central Ohio | $68,048,540 |
| Goodwill Industries of Central Ohio Inc | $59,254,949 |
| Community Shelter Board | $56,167,828 |
| Southeast Inc | $52,072,951 |
| Ohio Association of Foodbanks | $50,044,722 |
| Ohiohealth Corporation | $47,997,638 |
| Alvis Inc | $45,211,932 |
| Ohio Dominican University | $44,983,803 |
| Nationwide Foundation | $44,958,118 |
| Ohio Capital Corporation for Housing | $44,517,215 |
| Columbus College of Art & Design | $44,236,374 |
| Ohio Medical Transportation Inc | $40,730,914 |
| Columbus Downtown Development Corporation | $40,677,402 |
| 1244 Pathways Financial Cui | $39,749,424 |
| Trust for the Life Ins and Hlth Pl for Collectively Brgnd Pblc Empls | $34,526,864 |
| First Community Village | $34,175,868 |
| Strs Ohio Tx Real Estate Investments Inc | $26,695,969 |
| The Methodist Retirement Center of Central Ohio | $23,760,645 |
| Ohio Hospital Association | $21,909,268 |
| Huntington Foundation | $21,634,900 |
| The Affordable Housing Trust for Columbus & Franklin County | $21,413,478 |
| Foundation of the Catholic Diocese of Columbus | $21,212,337 |
| Campus Partners for Community Urban Redevelopment | $21,114,029 |
| Trust for the City of Phoenix Arizona Post Employment Health Pla | $20,524,329 |
| Jay and Jeanie Schottenstein Foundation | $19,136,551 |
| Columbus Museum of Art | $13,954,674 |
| Ohio Child Care Resource and Referral Association | $10,291,653 |
| The Journey Foundation | $8,945,269 |
| Nisource Charitable Foundation | $1,763,220 |