| Yale University | New Haven | $8,452,768,034 |
| Yale New Haven Hospital | New Haven | $4,883,266,662 |
| Hartford Hospital | Hartford | $2,936,696,079 |
| Knights of Columbus | New Haven | $2,757,321,043 |
| Americares Foundation Inc | Stamford | $1,851,063,617 |
| Boehringer Ingelheim Cares Foundation Inc | Ridgefield | $1,345,230,626 |
| Yale New Haven Health Services Corporation | New Haven | $1,157,413,267 |
| Saint Francis Hospital and Medical Center | Hartford | $989,157,513 |
| Danbury Hospital | Danbury | $943,179,862 |
| Bridgeport Hospital | Bridgeport | $925,337,466 |
| Save the Children Federation Inc | Fairfield | $920,455,828 |
| General Electric Company Insurance Plan Trust Co V A Diamante | Norwalk | $913,945,910 |
| Stamford Hospital | Stamford | $908,887,549 |
| Hospital of Central Connecticut at New Britain General and Bradley Me | New Britain | $813,961,965 |
| Dalio Family Fund Inc | Westport | $806,892,040 |
| Hartford Healthcare Medical Group Specialists PLLC | Wethersfield | $771,555,785 |
| Northeast Medical Group Inc | Stratford | $724,565,068 |
| Hartford Health Care Corporation | Hartford | $714,767,257 |
| Svmc Holdings Inc | Bridgeport | $707,034,879 |
| Quinnipiac University | Hamden | $658,577,859 |
| Connecticut Childrens Medical Center | Hartford | $639,591,217 |
| William W Backus Hospital | Norwich | $630,733,409 |
| Greenwich Hospital | Greenwich | $591,780,458 |
| Sacred Heart University | Fairfield | $575,678,695 |
| Middlesex Hospital | Middletown | $562,648,390 |
| Fairfield University | Fairfield | $558,598,313 |
| Lawrence and Memorial Hospital Inc | New London | $533,941,525 |
| Midstate Medical Center | Meriden | $477,938,120 |
| Nuvance Health Medical Practice Ct Inc | Danbury | $456,596,999 |
| Wesleyan University | Middletown | $443,190,970 |
| Norwalk Hospital Association | Norwalk | $439,338,450 |
| University of New Haven | West Haven | $392,215,175 |
| Saint Marys Hospital Inc | Hartford | $374,354,376 |
| The Mercy Hospital Inc | Hartford | $333,936,584 |
| Peter and Carmen Lucia Buck Foundation Inc | Mystic | $331,422,950 |
| University of Hartford | West Hartford | $305,633,140 |
| Common Fund for Non-Profit Organizations | Wilton | $288,654,386 |
| Trinity College | Hartford | $281,005,704 |
| The Griffin Hospital | Derby | $273,659,100 |
| Trinity Health of New England Provider Network Organization Inc | Hartford | $273,364,186 |
| Stamford Health Medical Group Inc | Stamford | $267,602,499 |
| Hartford Healthcare Medical Group Inc | Wethersfield | $243,367,330 |
| Charlotte Hungerford Hospital | Torrington | $224,723,970 |
| Connecticut Childrens Specialty Group Inc | Hartford | $190,295,976 |
| Achievement First Brooklyn Charter Schools | New Haven | $187,217,445 |
| Connecticut College | New London | $185,831,000 |
| Community Health Center Incorporated | Middletown | $181,241,894 |
| Trinity Health of New England Corporation Inc | Hartford | $175,906,147 |
| Bristol Hospital Incorporated | Bristol | $175,205,210 |
| Hartford Healthcare at Home Inc | Wethersfield | $153,240,296 |
| Coordinated Transportation Solutions Inc | Trumbull | $152,911,126 |
| Ufcw and Participating Employers New England Health Fund | Westport | $151,860,719 |
| Tri State Joint Fund | Cheshire | $149,383,842 |
| Greater Hartford Gives Foundation | Hartford | $144,403,277 |
| Hospital for Special Care | New Britain | $140,504,354 |
| Greenwich Country Day School Inc | Greenwich | $139,744,713 |
| University of Connecticut Foundation Incorporated | Storrs | $139,327,144 |
| Steven & Alexandra Cohen Foundation Inc | Stamford | $138,232,432 |
| Day Kimball Healthcare Inc | Putnam | $136,549,242 |
| Connecticut Foodshare Inc | Wallingford | $128,745,294 |
| Windham Community Memorial Hospital Inc | Willimantic | $127,830,009 |
| The University of Bridgeport Inc | East Hartford | $127,552,067 |
| Lmw Healthcare Inc | New London | $127,386,402 |
| American Eagle Financial Credit Union Incorporated | East Hartford | $127,109,502 |
| Hotchkiss School | Lakeville | $126,383,221 |
| Cw Resources Inc | New Britain | $125,644,354 |
| Taft School Corporation | Watertown | $122,752,450 |
| The Connecticut Institute for the Blind Inc | Hartford | $116,081,684 |
| Cornell Scott Hill Health Corporation | New Haven | $114,541,588 |
| Alexion Access Foundation | New Haven | $110,240,463 |
| New England Electrical Workers Benefit Fund | Meriden | $106,338,784 |
| Gaylord Hospital Inc | Wallingford | $105,659,377 |
| University of Saint Joseph | West Hartford | $103,325,035 |
| Wheeler Clinic Inc | Plainville | $102,120,576 |
| Choate Rosemary Hall Foundation Incorporated | Wallingford | $99,339,717 |
| Zoom Foundation | Greenwich | $97,257,191 |
| Brunswick School Inc | Greenwich | $95,285,151 |
| Connecticut State Employees Credit Union Inc | Hartford | $92,698,522 |
| Riverbend Medical Group Inc | Hartford | $89,160,378 |
| Seedlings Foundation | Branford | $86,918,654 |
| Knights of Columbus Charitable Fund Inc | New Haven | $85,542,892 |
| Community Health Network of Connecticut Inc | Wallingford | $84,061,257 |
| Community Health Resources Inc | Windsor | $82,502,473 |
| International Union of Operating Engineers Welfare Fund 478 | Hamden | $81,911,055 |
| Loomis Institute | Windsor | $80,498,468 |
| Hartford Healthcare Endowment LLC | Hartford | $80,256,351 |
| Johnson Memorial Hospital Inc | Hartford | $79,160,080 |
| The Jewish Home for the Elderly of Fairfield County Inc | Bridgeport | $78,029,846 |
| Fair Haven Community Health Clinic Inc | New Haven | $77,949,115 |
| Financial Accounting Foundation | Norwalk | $74,918,586 |
| Sikorsky Financial Credit Union Inc | Stratford | $73,084,443 |
| Achievement First Rhode Island | New Haven | $70,976,598 |
| Ability Beyond Disability Inc | Bethel | $67,955,400 |
| Silver Hill Hospital Inc | New Canaan | $67,844,922 |
| Hampshire Foundation Inc | Hartford | $67,589,104 |
| Masonicare Health Center | Wallingford | $64,321,452 |
| Connecticut Laborers Health Fund | West Haven | $63,262,512 |
| National Shooting Sports Foundation Inc | Shelton | $62,951,102 |
| The Village for Families & Children Inc | Hartford | $62,453,430 |
| Goodwin University Inc | East Hartford | $62,415,063 |
| Albertus Magnus College | New Haven | $62,216,973 |
| Greenwich Academy Inc | Greenwich | $60,992,552 |
| Ll Global Inc | Windsor | $59,741,002 |
| Goodwill of Western and Northern Connecticut Inc | Bridgeport | $57,351,173 |
| Vassar Health Connecticut Inc | Sharon | $57,198,663 |
| Kent School Corporation | Kent | $56,703,992 |
| Optimus Health Care Inc | Stratford | $56,209,555 |
| Community Foundation for Greater New Haven | New Haven | $55,709,123 |
| Cohen Veterans Network Inc | Stamford | $54,713,909 |
| Greens Farms Academy Inc | Greens Farms | $53,717,683 |
| Ibt Local 191 Health Services & Insurance Plan | Bridgeport | $53,501,520 |
| Avon Old Farms School Inc | Avon | $53,223,165 |
| Miss Porters School Inc | Farmington | $53,059,482 |
| Church Homes Inc Congregational | Hartford | $52,297,436 |
| Connex Credit Union Inc | North Haven | $52,043,001 |
| Planned Parenthood of Southern New England Inc | New Haven | $50,503,423 |
| New England Health Care Employees Welfare Fund | Hartford | $50,097,755 |
| Salisbury School Inc | Salisbury | $49,768,685 |
| King School Incorporated | Stamford | $49,691,024 |
| American School for the Deaf | West Hartford | $48,480,100 |
| Community Renewal Team Inc | Hartford | $47,217,358 |
| Trustees of Westminster School Inc | Simsbury | $46,733,878 |
| Connecticut Childrens Foundation Inc | Hartford | $46,656,166 |
| Church Home of Hartford | Bloomfield | $46,367,231 |
| Hopkins School Incorporated | New Haven | $44,088,664 |
| Goodwill Industries of Southern New England Inc | North Haven | $43,957,048 |
| Norwich Free Academy | Norwich | $43,634,151 |
| Suffield Academy | Suffield | $43,335,195 |
| New Canaan Country School Inc | New Canaan | $43,304,417 |
| Nutmeg State Financial Credit Union | Rocky Hill | $42,153,342 |
| Young Mens Christian Association of Metropolitan Hartford Inc | Hartford | $41,144,170 |
| Elim Park Baptist Home Inc | Cheshire | $41,130,192 |
| McLean Affiliates Inc | Simsbury | $40,774,676 |
| Transportation Health Services and Insurance Plan 443 | New Haven | $40,447,222 |
| St Lukes Foundation Inc | New Canaan | $38,526,979 |
| Whitney Center Inc | Hamden | $38,082,346 |
| Teamsters Local 671 Health Services & Insurance Plan | Bloomfield | $37,944,826 |
| High Watch Recovery Center Inc | Kent | $37,384,394 |
| The Frederick Gunn School Incorporated | Washington | $36,703,517 |
| The Multiple Myeloma Research Foundation Inc | Norwalk | $36,523,356 |
| Masonicare at Ashlar Village Inc | Wallingford | $35,082,683 |
| National Organization for Rare Disorders Inc | Danbury | $34,577,196 |
| Duncaster Incorporated | Bloomfield | $33,528,329 |
| Oceanographic Research & Exploration Foundation | Westport | $33,475,838 |
| Covenant Living of Cromwell Inc | Cromwell | $32,481,321 |
| Canterbury School Incorporated | New Milford | $32,131,786 |
| Pomfret School Incorporated | Pomfret | $32,056,359 |
| Ethel Walker School Inc | Simsbury | $31,349,665 |
| Kingswood Oxford School Inc | West Hartford | $30,265,142 |
| Board of Trustees of the Sheffield Scientific School | New Haven | $29,252,563 |
| Dutch Point Credit Union Inc | Wethersfield | $28,947,570 |
| Knobloch Family Foundation | Fairfield | $23,070,417 |
| Fairfield Countys Community Foundation Inc | Norwalk | $21,278,159 |
| Mutual Security Credit Union Inc | Shelton | $20,187,778 |
| Western Connecticut Health Network Inc | Danbury | $16,818,830 |
| Halvorsen Family Foundation | Stamford | $15,475,263 |
| The Tow Foundation Inc | New Canaan | $14,366,606 |
| Newmans Own Foundation | Westport | $13,467,664 |
| Cil Realty Inc | Hartford | $11,980,158 |
| Jane and Daniel Och Family Foundation | Greenwich | $9,057,937 |
| F B Heron Foundation | New Haven | $8,390,805 |
| Jp Fletcher Foundation Inc | North Haven | $4,849,821 |
| Andrew J & Joyce D Mandell Family Foundation Inc | Newington | $4,361,849 |
| The Grossman Family Foundation | Cos Cob | $4,000,795 |
| Melville Charitable Trust Inc | New Haven | $3,804,620 |
| Synchrony Foundation | Stamford | $2,446,644 |
| Low Road Foundation | Sharon | $1,946,348 |
| Lone Pine Foundation Inc | Greenwich | $1,284,221 |
| The Horrigan Family Foundation | Darien | $683,505 |