Institute for Systems Biology
401 Terry Ave N, Seattle, WA · IRS data through FY2024
Revenue, expenses and net assets
Revenue Expenses Net assets
| Tax year | Revenue | Expenses | Net assets |
|---|---|---|---|
| FY2024 | $42,255,091 | $47,550,054 | $58,859,496 |
| FY2023 | $43,611,326 | $46,752,331 | $62,630,122 |
| FY2022 | $37,072,888 | $41,968,785 | $61,681,006 |
| FY2021 | $43,313,392 | $38,933,529 | $73,696,982 |
| FY2020 | $39,847,320 | $40,513,307 | $67,161,593 |
| FY2019 | $36,230,866 | $41,016,030 | $63,505,387 |
| FY2018 | $31,249,334 | $33,125,028 | $63,067,652 |
| FY2017 | $31,226,281 | $31,854,012 | $71,749,749 |
| FY2016 | $87,151,283 | $32,600,250 | $70,872,485 |
| FY2015 | $31,520,035 | $33,241,519 | $14,509,621 |
| FY2014 | $31,664,045 | $33,423,718 | $16,216,019 |
| FY2013 | $45,826,260 | $41,674,522 | $18,038,454 |
| FY2012 | $43,651,357 | $44,210,577 | $12,175,674 |
| FY2011 | $38,802,723 | $47,590,897 | $12,834,894 |
Form 990 filings
The returns filed by Institute for Systems Biology (EIN 91-2003593), including Form 990 PDFs and e-file data by year, are available in ProPublica's Nonprofit Explorer. The figures on this page come from IRS data files built from those returns.
Where the revenue came from
| Source | Amount | % of revenue |
|---|---|---|
| Contributions & grants | $37,859,571 | 90% |
| Program service revenue | $822,273 | 2% |
| Other revenue | $3,573,247 | 8% |
Where the money was spent
| Category | Amount | % of expenses |
|---|---|---|
| Program services | $33,822,669 | 71% |
| Management & general | $13,295,843 | 28% |
| Fundraising | $431,542 | 1% |
What the numbers show
- Contributions & grants made up 90% of total revenue in FY2024.
- Program services accounted for 71% of functional expenses, management & general 28%, and fundraising 1%.
- 71% of functional expenses went to program services in FY2024. That is higher than 19.9% of 171 Science & Technology organizations nationwide (too few in WA for a state comparison).
- Net assets covered about 14.9 months of expenses at the end of the reporting year. That puts it in the 63rd percentile among 60 Science & Technology organizations in WA.
- Total revenue was higher than 98.4% of 62 Science & Technology organizations in WA.
- Total revenue rose from $38,802,723 in FY2011 to $42,255,091 in FY2024. Revenue increased in 8 and decreased in 5 of 13 year-over-year comparisons.
- Expenses exceeded revenue in 11 of 14 reported years (FY2011, FY2012, FY2014, FY2015, FY2017, FY2018, FY2019, FY2020, FY2022, FY2023, FY2024).
- The highest revenue on record here is $87,151,283 in FY2016.
- Net assets grew from $12,834,894 to $58,859,496 between FY2011 and FY2024.
- Contributions and grants made up 62% of revenue in FY2011 and 90% in FY2024.
- Listed in the IRS Publication 78 data as eligible to receive tax-deductible contributions (public charity).
Figures compared against other organizations of the same NTEE program area in the same state. See the methodology page for how these are calculated and the guide to reading nonprofit financials for their limits.
About this organization
USING THE SCIENCE OF SYSTEMS BIOLOGY TO PREDICT, PREVENT AND CURE DISEASE.
IRS status
| Ruling year | 2000 |
| Subsection | 501(c)(3) |
| Classification | Public charity |
| Program area (NTEE) | U500 — Science & Technology |
| Donations | Listed in the IRS Publication 78 data as eligible to receive tax-deductible contributions (public charity). |
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Source: Internal Revenue Service — Exempt Organizations Business Master File (downloaded November 4, 2026), Statistics of Income extracts, Form 990 e-file data, Publication 78 and the Automatic Revocation list. Figures are as reported by the organization; IRS processing may adjust them. This is not a charity rating and not tax advice. Confirm deductibility in IRS Tax Exempt Organization Search.
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