| Raymond James Charitable Endowment Fund | St Petersburg | $955,087,502 |
| Dechomai Foundation Inc | Jacksonville | $494,612,669 |
| Dechomai Asset Trust | Jacksonville | $459,598,859 |
| Betty Wold Johnson Foundation | West Palm Bch | $304,352,055 |
| Lowell S and Betty L Dunn Family Foundation | Hialeah Gdns | $266,901,803 |
| Isenberg Family Charitable Foundation Inc | Palm Beach | $178,857,843 |
| The Miami Foundation Inc | Miami | $156,012,967 |
| Greater Miami Jewish Federation | Miami | $135,322,419 |
| Community Foundation of Tampa Bay Inc | Tampa | $131,545,267 |
| The Community Foundation for Northeast Florida Inc | Jacksonville | $112,310,767 |
| The Invisible Hand Foundation | Miami | $104,966,401 |
| Jacarlene Foundation | Winter Park | $97,042,335 |
| Community Foundation of Sarasota County Inc | Sarasota | $87,039,125 |
| Gulf Coast Community Foundation Inc | Venice | $73,452,871 |
| United Way Miami Inc | Miami | $71,675,535 |
| Jupiter Medical Center Foundation Inc | Jupiter | $69,231,671 |
| Barbara Newington Foundation | Palm Beach | $65,798,356 |
| Givewell Community Foundation Inc | Lakeland | $63,733,787 |
| Community Foundation of Broward Inc | Fort Lauderdale | $55,146,534 |
| Jewish Federation of Palm Beach County Inc | West Palm Bch | $54,678,950 |
| Community Foundation for Palm Beach & Martin Counties Inc | West Palm Bch | $51,053,462 |
| Naples Children Foundation Inc | Naples | $47,618,532 |
| Ronald & Joyce Wanek Foundation Ltd | Tampa | $45,632,873 |
| Jim Moran Foundation Inc | Deerfield Bch | $45,240,979 |
| Cloverfields Foundation | Naples | $43,339,492 |
| Kovner Foundation | Jupiter | $43,099,460 |
| The Frederick A Deluca Foundation Inc | Pompano Beach | $42,638,258 |
| Screaming Comet Foundation | Miami Beach | $36,199,361 |
| Southwest Florida Community Foundation Inc | Fort Myers | $31,414,260 |
| Charles and Margery Barancik Foundation | Sarasota | $29,772,485 |
| Paulson Family Foundation | West Palm Bch | $28,195,371 |
| Jewish Federation of South Palm Beach County Inc | Boca Raton | $27,886,533 |
| United Way of Northeast Florida Inc | Jacksonville | $25,954,027 |
| United Jewish Community of Broward County Inc | Davie | $25,844,580 |
| Nonnas Garden A Private Foundation | Orlando | $25,818,726 |
| Volunteer Florida Foundation Inc | Tallahassee | $24,948,027 |
| Wonderful Life Foundation | West Palm Bch | $21,461,686 |
| Florida Gulf Coast University Financing Corporation | Fort Myers | $20,731,220 |
| Bravo Family Charitable Foundation | Miami | $19,078,243 |
| E G Watkins Family Foundation | West Palm Bch | $18,682,517 |
| Thomas W Smith Foundation | Boca Raton | $18,355,087 |
| Arison Arts Foundation | Coral Gables | $15,345,445 |
| Leslie L Alexander Foundation | Delray Beach | $15,030,809 |
| The Patterson Foundation | Sarasota | $14,565,549 |
| Truist Foundation Inc | Orlando | $13,948,262 |
| Peterffy Foundation | Fort Lauderdale | $13,833,456 |
| The Leandro P Rizzuto Foundation | Boynton Beach | $13,498,494 |
| Trish Joy Foundation for Humanitarian Activity | Clearwater | $13,294,626 |
| Dr Phillips Inc | Orlando | $13,134,733 |
| Pentecost Foundation | Bradenton | $12,653,160 |
| Ds Foundation | Miami | $11,847,310 |
| Albert L Ueltschi Foundation | Vero Beach | $11,732,631 |
| Micky and Madeleine Arison Family Foundation | Coral Gables | $11,262,728 |
| Mitchell Wolfson Sr Foundation | Miami | $11,139,861 |
| J Christopher and Anne N Reyesfoundation | West Palm Bch | $10,647,753 |
| Taft Foundation | Fort Lauderdale | $9,589,359 |
| Sage & Dice Foundation | Naples | $9,254,465 |
| George Jenkins Foundation Inc | Lakeland | $7,461,367 |
| David A Straz Jr Foundation | Tampa | $6,490,894 |
| The Seaman Foundation Inc | Seffner | $6,051,041 |
| Bernard A Egan Foundation Inc | Fort Pierce | $4,537,933 |
| Abramson Family Foundation | Jupiter | $2,923,470 |
| Harry T Mangurian Jr Foundation Inc | Ft Lauderdale | $2,724,472 |
| Marvin H Weiner Foundation Inc | Ft Lauderdale | $2,430,880 |
| The Fairholme Foundation | Coral Gables | $1,279,606 |
| Weston Family Foundation | Naples | $280,150 |
| Theodore R & Vivian M Johnson Scholarship Foundation Inc | West Palm Bch | $247,796 |
| Charles R Schwab Foundation for Financial Freedom | Palm Beach | $241,594 |
| Blue Cross and Blue Shield of Florida Foundation Inc | Jacksonville | -$1,508,267 |