| Organization | City | Revenue |
|---|
| Prisma Health Medical Group-Midlands | Greenville | $401,120,303 |
| Charter Institute at Erskine | Columbia | $299,875,169 |
| Furman University | Greenville | $296,850,871 |
| Anderson University | Anderson | $177,419,350 |
| Charleston Southern University | N Charleston | $125,239,964 |
| Clemson University Foundation | Clemson | $118,572,121 |
| Bju Inc | Greenville | $114,827,246 |
| University of South Carolina Educational Foundation | Columbia | $85,063,683 |
| North Greenville University | Tigerville | $72,415,205 |
| South Carolina First Steps to School Readiness Board of Trustees | Columbia | $72,391,847 |
| Columbia International University | Columbia | $71,013,416 |
| Claflin University | Orangeburg | $69,308,578 |
| Newberry College | Newberry | $66,284,560 |
| Benedict College | Columbia | $52,764,064 |
| Converse University | Spartanburg | $50,688,632 |
| Erskine College | Due West | $47,967,931 |
| Meeting Street Schools | Charleston | $46,778,434 |
| Limestone University | Gaffney | $46,519,696 |
| University of South Carolina School of Medicine Educational Trust | Columbia | $44,237,810 |
| Christ Church Episcopal School | Greenville | $44,124,234 |
| Citadel Foundation | Charleston | $37,924,388 |
| Securing Assets for Education | Moncks Corner | $26,810,615 |
| Scago Educational Facilities Corporation for Pickens School Dis | Easley | $22,003,623 |
| Building Equity Sooner for Tomarrow | Greenville | $14,194,205 |
| Beemok Family Foundation | Charleston | $3,874,618 |