| Mainehealth | Portland | $4,705,659,409 |
| Eastern Maine Healthcare Systems | Brewer | $1,267,521,596 |
| Mainegeneral Health | Augusta | $787,029,171 |
| Martins Point Generations Advantage Inc | Portland | $745,845,935 |
| Jackson Laboratory | Bar Harbor | $652,542,607 |
| Maine Education Association Benefits Trust | Augusta | $599,325,980 |
| Martins Point Health Care Inc | Portland | $550,076,243 |
| Central Maine Medical Center | Lewiston | $547,503,452 |
| Eastern Maine Healthcare Systems | Brewer | $473,110,808 |
| Bowdoin College | Brunswick | $449,569,000 |
| Mercy Hospital | Brewer | $372,070,489 |
| President & Trustees of Colby College | Waterville | $354,489,000 |
| University of New England | Biddeford | $322,835,606 |
| Maine Community Health Options | Lewiston | $303,837,975 |
| President and Trustees of Bates College | Lewiston | $242,157,257 |
| St Marys Regional Medical Center | Lewiston | $236,199,865 |
| Employees of Municipal & Other Pub- Lic Employers of Me Health Ins Tr | Augusta | $213,362,776 |
| York Hospital | York | $205,401,645 |
| Eastern Maine Healthcare Systems | Brewer | $185,132,644 |
| Redington-Fairview General Hospital | Skowhegan | $176,287,088 |
| New England Life Care Inc | Scarborough | $154,228,536 |
| Maine Community Foundation Inc | Ellsworth | $138,801,505 |
| Maine Coast Regional Health Facili Dba Northern Light Maine Coast Hos | Brewer | $130,321,076 |
| Maine Veterans Home | Augusta | $119,340,649 |
| Nordx | Scarborough | $118,490,275 |
| Harold Alfond Foundation | Portland | $110,997,249 |
| Good Sheperd Food Bank | Auburn | $104,490,942 |
| Penobscot Community Health Center | Bangor | $102,890,473 |
| Mount Desert Island Hospital | Ben Harbor | $101,028,358 |
| Eastern Maine Healthcare Systems | Brewer | $98,070,771 |
| Spurwink Services Incorporated | Scarborough | $96,383,218 |
| Husson University | Bangor | $94,887,660 |
| Goodwill Industries of Northern New England | Gorham | $93,335,985 |
| Unity Environmental University | New Gloucester | $86,719,160 |
| Northern Maine Medical Center | Fort Kent | $84,798,967 |
| Maine Guaranteed Access Reinsurance Association | Portland | $79,759,393 |
| Blue Horizons Foundation | Gorham | $79,229,574 |
| John F Murphy Homes Inc | Auburn | $79,166,252 |
| Eastern Maine Healthcare Systems | Brewer | $72,943,256 |
| Penquis C A P Inc | Bangor | $71,166,555 |
| Central Maine Healthcare Corporation | Lewiston | $68,708,052 |
| Eastern Maine Healthcare Systems | Brewer | $66,898,130 |
| Androscoggin Home Health Services Inc | Lewiston | $65,364,056 |
| Down East Community Hospital | Machias | $64,811,794 |
| University of Maine Foundation | Orono | $60,444,315 |
| Bridgton Hospital | Bridgton | $59,810,637 |
| Sweetser | Saco | $54,709,980 |
| Trustees of St Josephs College | Standish | $54,603,399 |
| Thomas College | Waterville | $41,372,529 |
| Blue Hill Memorial Hospital Inc | Brewer | $39,496,902 |
| Lunder Foundation | Portland | $38,327,642 |
| Maine Life Care Retirement Community Inc | Scarborough | $36,977,131 |
| Eastern Maine Healthcare Systems | Brewer | $33,409,661 |
| Evergreen Credit Union | Portland | $33,224,947 |
| College of the Atlantic | Bar Harbor | $31,939,740 |
| Bigelow Laboratory for Ocean Sciences | East Boothbay | $29,714,759 |
| Td Charitable Foundation | Portland | $25,145,042 |
| Maine Coast Heritage Trust | Topsham | $21,977,989 |
| Coastal Enterprises Inc | Brunswick | $19,896,255 |
| Mainhealth Services | Portland | $19,103,467 |
| John T Gorman Foundation | Portland | $13,301,002 |
| Firebird Foundation for Anthropological Research Inc | Phillips | $5,963,118 |
| Elmina B Sewall Foundation | Freeport | $5,294,917 |
| Housing Initiatives of New England | Scarborough | $4,720,182 |