| Ochsner Clinic Foundation | New Orleans | $6,038,885,387 |
| Our Lady of the Lake Hospital Inc | Baton Rouge | $2,236,247,950 |
| The Administrators of the Tulane Educational Fund | New Orleans | $1,943,508,000 |
| Willis-Knighton Medical Center | Shreveport | $1,694,008,878 |
| Louisiana Childrens Medical Center | New Orleans | $1,635,655,698 |
| Ochsner LSU Health System of North Louisiana | Shreveport | $1,093,086,473 |
| Womans Hospital Foundation | Baton Rouge | $1,003,943,473 |
| University Medical Center Management Corporaton | New Orleans | $792,867,500 |
| Childrens Hospital Inc | New Orleans | $737,323,254 |
| Lafayette General Medical Center Inc | Lafayette | $734,876,253 |
| Baton Rouge General Medical Center | Baton Rouge | $712,345,722 |
| Our Lady of Lourdes Regional Medical Center Inc | Baton Rouge | $692,798,699 |
| Southwest Louisiana Hospital Association Inc | Lake Charles | $534,408,606 |
| St Francis Medical Center Inc | Baton Rouge | $519,451,851 |
| Christus Health Central Louisiana | Alexandria | $471,326,798 |
| Franciscan Missionaries of Our Lady Health System Inc | Baton Rouge | $445,304,404 |
| Thibodaux Regional Health System Inc | Thibodaux | $382,055,537 |
| Touro Infirmary | New Orleans | $367,303,040 |
| Christus Health Northern Louisiana | Shreveport | $366,092,739 |
| Provident Resources Group Inc | Baton Rouge | $356,142,236 |
| Southwest Louisiana Electric | Lafayette | $320,484,167 |
| Mary Bird Perkins Cancer Center | Baton Rouge | $318,045,658 |
| Christus Health Southwestern Louisiana | Lake Charles | $303,494,087 |
| Lafayette General Health System Inc | Lafayette | $301,428,641 |
| Dixie Electric Membership Corporation | Greenwel Spgs | $274,490,843 |
| Loyola University | New Orleans | $225,282,245 |
| Louisiana Insurance Guaranty Association | Baton Rouge | $222,880,537 |
| Commcare Corporation | Mandeville | $220,293,466 |
| LSU Health Sciences Center - Shreveport Faculty Group Practice | Shreveport | $214,218,561 |
| University Hospital & Clinics Inc | Lafayette | $189,555,088 |
| Beauregard Electric Cooperative Inc | Deridder | $162,960,883 |
| Xavier University of Louisiana | New Orleans | $154,096,177 |
| Louisiana State University of Medicine in New Orleans | New Orleans | $144,307,672 |
| General Health System | Baton Rouge | $139,903,868 |
| Tiger Athletic Foundation | Baton Rouge | $123,859,705 |
| L S U Foundation | Baton Rouge | $121,135,454 |
| Washington-St Tammany Electric Cooperative Inc 1570 | Franklinton | $119,441,613 |
| KIPP New Orleans Inc | New Orleans | $113,024,960 |
| National World War II Museum Inc | New Orleans | $95,221,388 |
| Second Harvest Food Bank of Greater New Orleans and Acadiana | New Orleans | $91,290,505 |
| Inspirenola Charter Schools | New Orleans | $89,877,052 |
| State Chartered Credit Unions in Louisiana | Baton Rouge | $88,451,502 |
| No AIDS Task Force | New Orleans | $88,042,103 |
| Lafayette Charter Foundation Inc | Lafayette | $79,267,611 |
| Our Lady of the Angels Hospital Inc | Baton Rouge | $79,193,019 |
| Lafourche Parish Hospital Service District No 1 | Cut Off | $74,460,182 |
| Claiborne Electric Cooperative Inc | Homer | $73,528,200 |
| Evergreen Presbyterian Ministries Inc | Haughton | $71,411,229 |
| The Greater New Orleans Foundation | New Orleans | $67,571,509 |
| Collegiate Academies | New Orleans | $64,522,864 |
| New Orleans Jazz & Heritage Foundation Inc | New Orleans | $61,887,065 |
| Arkansas Elder Outreach of Little Rock Inc | Baton Rouge | $61,566,299 |
| New Orleans & Company | New Orleans | $60,956,868 |
| Louisiana Organ Procurement Agency | Covington | $60,534,270 |
| Baton Rouge Area Foundation | Baton Rouge | $56,922,835 |
| Louisiana United Methodist Children and Family Services Inc | Ruston | $54,662,654 |
| Ragin Cajun Facilities Inc | Lafayette | $53,212,091 |
| The Alta and John Franks Foundation | Shreveport | $52,431,190 |
| Community School for Apprenticeship Learning Inc | Baton Rouge | $52,127,791 |
| Dillard University | New Orleans | $50,720,584 |
| Foundation for Louisiana Students | Baton Rouge | $50,548,458 |
| Lifeshare Blood Center | Shreveport | $47,726,980 |
| Centenary College of Louisiana | Shreveport | $46,846,087 |
| Georgia Protoncare Center | Baton Rouge | $45,780,781 |
| Isidore Newman School | New Orleans | $44,537,984 |
| Goodwill Industries of Southeastern Louisiana Inc | New Orleans | $42,123,611 |
| University of Louisiana at Lafayette Foundation | Lafayette | $41,784,322 |
| Goldring Family Foundation | Metairie | $40,304,263 |
| St Martin Hospital Inc | Breaux Bridge | $38,975,979 |
| Lake Charles Charter Academy Foundation Inc | Lake Charles | $38,064,894 |
| Jefferson Davis Electric Coop Inc | Jennings | $34,402,281 |
| St James Place of Baton Rouge | Baton Rouge | $33,322,496 |
| Gulf Coast Housing Partnership Inc | Kenner | $32,351,359 |
| Lctcs Facilities Corporation | Metairie | $32,204,830 |
| Community Foundation of Acadiana | Lafayette | $31,703,440 |
| Community Foundation of North Louisiana | Shreveport | $28,609,748 |
| Louisiana College | Pineville | $28,407,416 |
| St Bernard Hospital Foundation Inc | Chalmette | $27,798,431 |
| Stuller Family Foundation | Lafayette | $27,441,866 |
| Biomedical Research Foundation of Northwest Louisiana | Shreveport | $25,307,433 |
| Louisiana Tech University Foundation Inc | Ruston | $23,966,271 |
| Marshall Legacy Foundation | Metairie | $15,687,056 |
| LSU Health Sciences Foundation in Shreveport | Shreveport | $14,316,771 |
| Baptist Community Ministries | New Orleans | $13,238,047 |
| Gayle and Tom Benson Charitablefoundation | Metairie | $7,418,203 |
| Huey and Angelina Wilson Foundation | Baton Rouge | $3,268,040 |
| Entergy Charitable Foundation | New Orleans | $2,978,243 |