| Florida Health Sciences Center Inc | $3,809,952,749 |
| H Lee Moffitt Cancer Center and Research Institute Hospital Inc | $2,640,684,525 |
| Shriners Hospitals for Children | $1,582,506,437 |
| University Community Hospital Inc | $1,372,221,067 |
| Suncoast Credit Union | $1,106,877,469 |
| Baycare Medical Group Inc | $705,286,408 |
| Can Community Health Inc | $506,024,240 |
| University Medical Service Association Inc | $493,985,662 |
| University of Tampa | $493,753,503 |
| Uma Education Inc | $457,258,968 |
| Lutheran Services Florida Inc | $443,658,918 |
| Florida Hospital Physician Group Inc | $327,676,671 |
| H Lee Moffitt Cancer Center and Research Institute Inc | $322,301,135 |
| Central Florida Behavioral Health Network Inc | $304,199,504 |
| Feeding America Tampa Bay Inc | $211,887,087 |
| Lifelink Foundation Inc | $205,771,733 |
| University of South Florida Foundation Inc | $187,811,816 |
| H Lee Moffitt Cancer Ctr & Res Inst Life Time Cancer Scrn Ctr Inc | $173,244,422 |
| Community Foundation of Tampa Bay Inc | $131,545,267 |
| Hillsborough County School Readiness Coalition Inc | $127,649,758 |
| Aaa Scholarship Foundation Inc | $104,400,455 |
| Tampa Family Health Centers Inc | $96,797,150 |
| Tampa General Medical Group Inc | $85,626,581 |
| The Shriners Hospital for Children | $73,946,079 |
| Big Brothers Big Sisters of America | $69,170,417 |
| Tampa Bay Performing Arts Center | $59,953,966 |
| Ibis Healthcare Inc | $59,786,274 |
| Amikids Inc | $56,885,371 |
| Amikids Inc | $54,160,827 |
| Arbitration Forums Inc | $52,985,844 |
| Tampa Metropolitan Area Young Mens Christian Association Inc | $51,383,398 |
| Metropolitan Ministries Inc | $49,650,309 |
| Lowry Park Zoological Society of Tampa Inc | $48,990,299 |
| Ronald & Joyce Wanek Foundation Ltd | $45,632,873 |
| H Lee Moffitt Cancer Center and Research Institute Foundation Inc | $41,320,097 |
| Florida Aquarium Inc | $37,200,637 |
| Special Operations Warrior Foundation | $32,903,479 |
| State Chartered Credit Unions in Florida | $31,798,268 |
| Usf Financing Corporation | $30,142,277 |
| St Josephs Health Care Center Inc | $27,543,180 |
| David A Straz Jr Foundation | $6,490,894 |
| Vinik Family Foundation | -$16,722,111 |