| Genentech Patient Foundation | S San Fran | $3,634,462,791 |
| William & Flora Hewlett Foundation | Menlo Park | $605,258,937 |
| Sergey Brin Family Foundation | San Francisco | $430,295,656 |
| Gordon E and Betty I Moore Foundation | Palo Alto | $408,113,771 |
| David and Lucile Packard Foundation | Los Altos | $371,574,675 |
| Good Ventures Foundation | Palo Alto | $369,384,206 |
| The California Endowment | Los Angeles | $350,281,327 |
| The Eric and Wendy Schmidt Fund for Strategic Innovation | Palo Alto | $301,970,372 |
| Carl Victor Page Memorial Foundation | Palo Alto | $285,596,584 |
| Sequoia Climate Foundation | Irvine | $257,446,975 |
| Gerson Bakar Foundation | San Francisco | $255,406,561 |
| Waverley Street Foundation | Palo Alto | $225,507,334 |
| Benificus Foundation | San Carlos | $220,068,974 |
| Conrad N Hilton Foundation | Westlake Vlg | $210,298,805 |
| The Annenberg Foundation | Los Angeles | $200,588,922 |
| H&H Evergreen Foundation | Menlo Park | $183,666,500 |
| James Irvine Foundation | San Francisco | $177,075,927 |
| The Heising-Simons Foundation | Los Altos | $164,266,528 |
| Crankstart Foundation | San Jose | $159,771,106 |
| The Schmidt Family Foundation | Palo Alto | $137,609,510 |
| The David Geffen Foundation | Los Angeles | $129,741,899 |
| Broad Foundation | Los Angeles | $129,246,056 |
| Valhalla Foundation | Woodside | $127,956,635 |
| Tosa Foundation | Portola Vally | $88,885,636 |
| Koum Family Foundation | Palo Alto | $83,981,370 |
| Skyline Foundation | Palo Alto | $80,682,614 |
| Dart-L Foundation | Los Angeles | $75,180,000 |
| Breakthrough Prize Foundation | Los Angeles | $72,147,195 |
| Resnick Foundation | Los Angeles | $71,576,535 |
| John H and Regina K Scully Foundation | San Rafael | $70,276,471 |
| Sobrato Family Foundation | Mountain View | $65,635,935 |
| Anderson Stewart Family Foundation | Los Angeles | $65,445,000 |
| Jen-Hsun & Lori Huang Foundation | Palo Alto | $59,723,672 |
| The California Wellness Foundation | Los Angeles | $59,641,358 |
| W M Keck Foundation | Los Angeles | $59,628,353 |
| Rippleworks Inc | San Francisco | $58,579,920 |
| Wayne & Gladys Valley Charitable Foundation | Oakland | $57,971,000 |
| Chan Zuckerberg Initiative Foundation | Palo Alto | $57,960,663 |
| Stupski Foundation | San Francisco | $57,704,853 |
| Aphorism Foundation | San Francisco | $55,144,755 |
| The Larry Ellison Foundation | Walnut Creek | $53,874,000 |
| Conrad Prebys Foundation | San Diego | $53,715,018 |
| Kataly Foundation | San Francisco | $53,092,700 |
| The Ahmanson Foundation | Beverly Hills | $51,151,890 |
| Hellman Foundation | San Francisco | $49,961,776 |
| Koret Foundation | San Francisco | $46,948,842 |
| Roberts Foundation | San Mateo | $45,741,340 |
| Sea Change Foundation | San Francisco | $45,537,500 |
| Craig Newmark Foundation | San Francisco | $43,304,000 |
| Charles and Helen Schwab Foundation | San Francisco | $40,875,089 |
| Weingart Foundation | Los Angeles | $39,748,116 |
| Enlight Foundation | Palo Alto | $39,613,833 |
| Skoll Foundation | San Francisco | $39,551,867 |
| The Marisla Foundation | Laguna Beach | $39,442,814 |
| Shimon Ben Joseph Foundation | San Francisco | $37,719,275 |
| Oprah Winfrey Charitable Foundation | Los Angeles | $37,488,904 |
| Hobson Lucas Family Foundation | San Rafael | $36,959,612 |
| Salesforce Com Foundation | San Francisco | $36,145,900 |
| Xie Foundation | Sunnyvale | $35,368,429 |
| Visa Foundation | San Francisco | $35,053,968 |
| Samueli Foundation | Corona Dl Mar | $34,546,542 |
| Craig H Neilsen Foundation | Calabasas | $34,434,977 |
| Arnold and Mabel Beckman Foundation | Irvine | $33,731,217 |
| Autodesk Foundation | San Francisco | $33,000,000 |
| Jeff and Marieke Rothschild Foundation | Palo Alto | $32,909,567 |
| Cortopassi Family Foundation | Stockton | $32,105,275 |
| Cisco Systems Foundation | San Jose | $30,414,677 |
| The Amgen Foundation Inc | Newbury Park | $30,031,820 |
| Libra Foundation | San Francisco | $30,000,000 |
| Gene Haas Foundation | Oxnard | $29,532,163 |
| Delta Dental Community Care Foundation | San Francisco | $28,998,462 |
| Priem Family Foundation | Burlingame | $28,987,743 |
| Gary and Mary West Charitable Trust | La Jolla | $28,891,826 |
| Karsh Family Foundation | Beverly Hills | $28,706,900 |
| Alfred E Mann Charities Inc | San Fernando | $28,577,182 |
| Open Doors International Inc | Orange | $27,818,635 |
| Omidyar Network Fund Inc | San Francisco | $27,224,915 |
| Sunlight Giving | Palo Alto | $27,010,471 |
| Diane and Guilford Glazer Foundation | Beverly Hills | $25,976,136 |
| Imaginable Futures Foundation | Redwood City | $25,931,492 |
| Capital Group Companies Charitable Foundation | Irvine | $25,756,751 |
| Saul Brandman Foundation | Beverly Hills | $25,289,091 |
| Smidt Foundation | Beverly Hills | $24,765,320 |
| Anne Wojcicki Foundation | Los Altos | $24,750,612 |
| Windsong Tr | Manhattan Bch | $24,477,171 |
| Evelyn and Walter Haas Jr Fund | San Francisco | $24,426,856 |
| Gilead Sciences Foundation | Foster City | $23,843,719 |
| Elbridge Stuart Foundation | San Francisco | $23,721,025 |
| Michael and Lori Milken Family Foundation | Santa Monica | $22,836,303 |
| Mercury Foundation | Redwood City | $22,500,000 |
| Dhanam Foundation | Palo Alto | $22,373,600 |
| Hopper-Dean Foundation | Menlo Park | $22,094,900 |
| Additional Ventures Foundation | San Francisco | $21,809,416 |
| Ressler Gertz Foundation | Sherman Oaks | $21,757,600 |
| J Paul Getty Trust | Los Angeles | $21,448,331 |
| Argyros Family Foundation | Costa Mesa | $20,970,207 |
| Lisa and Douglas Goldman Fund | San Francisco | $20,671,554 |
| Lakeshore Foundation 04052011 | Redwood City | $20,660,000 |
| Xq Institute | Palo Alto | $20,200,043 |
| May and Stanley Smith Charitable Trust | Larkspur | $20,140,417 |
| The Leonard and Sophie Davis Fund | San Francisco | $20,132,020 |
| William S and Nancy E Thompson Foundation | Irvine | $19,913,224 |
| Kavli Foundation | Los Angeles | $19,810,112 |
| Humanity United | San Francisco | $19,599,701 |
| Chuck Lorre Family Foundation | Los Angeles | $19,306,839 |
| Ralph M Parsons Foundation | Los Angeles | $19,158,966 |
| Price Philanthropies Foundation | La Jolla | $18,885,464 |
| Oberndorf Family Foundation | San Francisco | $18,866,500 |
| Woka Foundation | Newbury Park | $18,822,188 |
| Gross Family Charitable Foundation | Laguna Beach | $18,028,808 |
| California Physicians Service Foundation | San Francisco | $17,819,396 |
| College Futures Foundation | Oakland | $17,646,850 |
| Troper Wojcicki Foundation | San Francisco | $17,595,579 |
| Artnow International Inc | San Francisco | $17,474,359 |
| Pg&E Corporation Foundation | Oakland | $17,365,835 |
| Patrick F Cadigan Family Foundation | Newport Beach | $17,250,000 |
| Pwb Foundation | San Francisco | $17,250,000 |
| Panda Charitable Family Foundation | Rosemead | $16,804,352 |
| John Pritzker Family Fund | Redwood City | $16,604,317 |
| The Grove Foundation | Los Altos | $16,206,689 |
| Massiah Foundation Inc | Newport Beach | $16,045,589 |
| Jeffrey Carlton Charitable Foundation Udt Dated April 10 2009 | Villa Park | $16,000,000 |
| Kenneth Rainin Foundation | Oakland | $15,924,987 |
| Rosalinde and Arthur Gilbert Foundation | Los Angeles | $15,757,096 |
| Johnny Carson Foundation | Encino | $15,466,600 |
| The Chan Soon-Shion Family Foundation | Los Angeles | $15,349,025 |
| Fritz B Burns Foundation | Woodland Hls | $15,275,000 |
| Esb Charitable Foundation | San Francisco | $14,660,000 |
| Jean & E Floyd Kvamme Foundation | Scotts Valley | $14,659,028 |
| Connie and Bob Lurie Foundation Inc | Redwood City | $14,516,275 |
| Thomas and Dorothy Leavey Foundation | Los Angeles | $14,166,545 |
| Rm Liu Family Foundation | Gardena | $14,046,000 |
| Mimi and Peter Haas Fund | San Francisco | $13,665,210 |
| Pisces Foundation | San Francisco | $13,663,788 |
| William G Irwin Charity Foundation | San Francisco | $13,608,734 |
| Lowell Milken Family Foundation | Santa Monica | $13,606,550 |
| Wasserman Foundation | Los Angeles | $13,598,144 |
| Simpson Foundation | Orinda | $13,592,525 |
| Cabin Road Foundation 04042011 | Redwood City | $13,520,000 |
| Walter and Elise Haas Fund | San Francisco | $13,451,206 |
| Intuitive Foundation | Sunnyvale | $13,413,768 |
| Helen and Will Webster Foundation | Arcadia | $13,327,866 |
| Kenneth T and Eileen L Norris Foundation | Torrance | $13,299,000 |
| Hp Foundation | Palo Alto | $13,201,623 |
| Christensen Fund | San Francisco | $13,098,050 |
| Jayasinhala Foundation | Los Angeles | $12,994,750 |
| Colburn Foundation | Los Angeles | $12,917,605 |
| The Walt and Lilly Disney Foundation | San Francisco | $12,759,657 |
| Michelson Medical Research Foundation Inc | Los Angeles | $12,492,560 |
| S L Gimbel Foundation | Orange | $12,240,553 |
| Clif Bar Family Foundation | Saint Helena | $12,047,980 |
| eBay Foundation | San Jose | $12,000,000 |
| Meadowview Foundation | San Rafael | $12,000,000 |
| Merkin Family Foundation | Marina Dl Rey | $11,734,000 |
| Helen and Sanford Diller Family Foundation | San Mateo | $11,648,307 |
| Bernard Osher Foundation | San Francisco | $11,544,340 |
| Shurl and Kay Curci Foundation | Torrance | $11,494,657 |
| Rodan Family Foundation | Orinda | $11,396,947 |
| Laural Foundation | San Francisco | $11,360,777 |
| The Hearthland Foundation | Los Angeles | $11,347,450 |
| David and Fela Shapell Family Foundation | Los Angeles | $11,323,650 |
| Eugene and Marilyn Stein Family Foundation | Hillsborough | $11,266,000 |
| Jmm Charitable Foundation Inc | Los Angeles | $11,162,019 |
| Gleason Family Foundation | Pine Grove | $11,024,824 |
| Kalmanovitz Charitable Foundation | Mill Valley | $10,918,513 |
| Perenchio Foundation | Pasadena | $10,902,000 |
| Sijbrandij Foundation | San Francisco | $10,790,127 |
| Give Forward Foundation | San Francisco | $10,649,870 |
| Gitlab Org Foundation | San Francisco | $10,617,000 |
| Maxwell Hanrahan Foundation | San Francisco | $10,613,449 |
| Fred Maytag Family Foundation | San Francisco | $10,462,332 |
| The Eisner Foundation Inc | Beverly Hills | $10,354,848 |
| Ross M Brown Family Foundation | Escondido | $10,318,830 |
| King Philanthropies Inc | Menlo Park | $10,243,600 |
| Doris & Donald Fisher Foundation | San Francisco | $10,220,000 |
| Sam Simon Charitable Giving Foundation Inc | Los Angeles | $10,217,000 |
| The Call of Duty Endowment | Agoura | $10,182,000 |
| Warren & Katharine Schlinger Foundation | Laguna Niguel | $10,050,000 |
| The Joseph and Vera Long Foundation | Walnut Creek | $10,011,800 |
| Dos Ranchos Preserve | Redlands | $10,000,000 |
| The Duffield Family Foundation | Pleasanton | $9,876,046 |
| Packard Humanities Institute | Los Altos | $9,835,277 |
| The Herb Alpert Foundation | Santa Monica | $9,819,700 |
| McConnell Foundation | Redding | $9,766,288 |
| Baszucki Family Foundation | San Mateo | $9,755,138 |
| Tarsadia Foundation | Newport Beach | $9,665,553 |
| 128 Collective Foundation | Palo Alto | $9,408,473 |
| Carrie Estelle Doheny Foundation | Los Angeles | $9,392,599 |
| Matthew and Iris Strauss Familyfoundation Inc | Solana Beach | $9,388,052 |
| Swenson Family Foundation | Orange | $9,361,880 |
| William K Bowes Jr Foundation | San Francisco | $9,290,452 |
| Irving and Elanor Jaffee Foundation Inc | San Diego | $9,281,142 |
| Levi Strauss Foundation | San Francisco | $9,238,262 |
| Colburn Music Fund | Los Angeles | $9,200,440 |
| Edwards Lifesciences Foundation | Irvine | $9,175,861 |
| Aam Foundation | Novato | $9,126,965 |
| John Martin Foundation | San Francisco | $9,036,404 |
| Carl and Roberta Deutsch Foundation | Santa Monica | $9,034,200 |
| The Herbert and Elaine Kendall Charitable Foundation | Los Angeles | $8,661,420 |
| Shillman Foundation | Rcho Santa Fe | $8,653,190 |
| Applied Materials Foundation | Santa Clara | $8,501,654 |
| Y & S Nazarian Family Foundation | Beverly Hills | $8,383,050 |
| Georg & Judy Marcus Family Foundation | Palo Alto | $8,340,740 |
| Mitchell Kapor Foundation | Oakland | $8,284,658 |
| Kelson Foundation | San Francisco | $8,262,971 |
| The Goldrich Family Foundation C/O Jona Goldrich | Culver City | $8,231,097 |
| Snap Foundation | Los Angeles | $7,967,368 |
| Quest Foundation | Danville | $7,947,162 |
| Dan Murphy Foundation | Los Angeles | $7,925,462 |
| H N and Frances C Berger Foundation | Palm Desert | $7,917,582 |
| Cotsen Foundation for the Art of Teaching | Los Angeles | $7,905,084 |
| The Green Foundation | Pasadena | $7,883,116 |
| Jonathan Logan Family Foundation | Berkeley | $7,875,900 |
| Wadhwani Institute for Artificial Intelligence Foundation | Los Altos | $7,757,862 |
| Wood-Claeyssens Foundation | Santa Barbara | $7,715,500 |
| Carina Initiatives Inc | Torrance | $7,561,145 |
| Otis Booth Foundation | Los Angeles | $7,525,175 |
| Laygend Foundation | Rcho Santa Fe | $7,500,000 |
| Fletcher Jones Foundation | Pasadena | $7,425,000 |
| Edgerton Foundation | Los Angeles | $7,415,000 |
| John and Marcia Goldman Foundation | San Francisco | $7,366,951 |
| Goldberg Family Foundation Inc | Beverly Hills | $7,250,000 |
| Henry T Nicholas III Foundation | Aliso Viejo | $7,212,781 |
| Carestar Foundation | Berkeley | $7,180,000 |
| Kalliopeia Foundation | Inverness | $6,706,000 |
| The Betty Bazar Foundation | Valencia | $6,101,868 |
| Jhm Charitable Foundation | Manhattan Bch | $6,027,431 |
| Shanahan Family Charitablefoundation | Pasadena | $5,844,977 |
| Lampert Fam Foundation Uta 121500 | San Francisco | $5,799,175 |
| Chuck and Ernestina Kreutzkamp Foundation | Chula Vista | $5,762,500 |
| Eucalyptus Foundation | San Francisco | $5,509,292 |
| Unihealth Foundation | Pasadena | $5,177,240 |
| Artemis Rising Foundation | San Rafael | $4,579,400 |
| Torrey Coast Foundation | San Diego | $4,376,685 |
| Pichai Family Foundation | San Francisco | $4,238,997 |
| Whh Foundation | San Marino | $4,146,785 |
| Sakana Foundation | San Francisco | $4,059,739 |
| Tandem Philanthropies | Santa Rosa | $2,750,800 |
| The 1440 Foundation | Saratoga | $2,145,162 |
| 1011 Foundation Inc | Santa Monica | $1,506,372 |
| Schmidt Ocean Institute | Palo Alto | $405,059 |
| Harold C and Marilyn A Hohbach Foundation | Palo Alto | $305,000 |
| Making Waves Foundation Inc | Richmond | $191,500 |
| Monterey Bay Aquarium Research Institute | Moss Landing | $100,000 |
| Broad Art Foundation | Los Angeles | $82,083 |
| Towbes Foundation | Santa Barbara | $23,900 |